Kennan Salinero [salinerok]
What do you investigate? What is at the heart of your research?
How we 'do' science
Do you have a link to a site where we can see something about you, or the center where you work?
What is your educational background? What work experience did you have before this?
Research, teaching, nonprofit formation
Did you keep your nose to the grindstone in school?
Yes but it was easy
What kind of technology are you using for your research right now?
Social media, communication
What types of experiments do you conduct? How are the conclusions documented?
Feedback loops - what paths lead to new connections and actions?
If you conclude your investigation successfully, what practical application would it have in everyday life?
Science and society both thriving.
What is a "eureka" moment? What is it like to experience one?
Chills - everything snaps into place. Wonderment.
What do you find to be the most difficult aspects of your research?
cynicism and resignation
What have you published?
Salinero KK, Keller K, Feil WS, Feil H, Trong S, Di Bartolo G, Lapidus A.
Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB:
indications of a surprisingly complex life-style and cryptic anaerobic pathways
for aromatic degradation. BMC Genomics. 2009 Aug 3;10:351. PubMed PMID: 19650930;
PubMed Central PMCID: PMC2907700.
Gilmore R, Collins P, Johnson J, Kellaris K, Rapiejko P. Transcription of
full-length and truncated mRNA transcripts to study protein translocation across
the endoplasmic reticulum. Methods Cell Biol. 1991;34:223-39. Review. PubMed
Kellaris KV, Bowen S, Gilmore R. ER translocation intermediates are adjacent
to a nonglycosylated 34-kD integral membrane protein. J Cell Biol. 1991
Jul;114(1):21-33. PubMed PMID: 1646822; PubMed Central PMCID: PMC2289059.
Gilmore R, Kellaris KV. Translocation of proteins across and integration of
membrane proteins into the rough endoplasmic reticulum. Ann N Y Acad Sci. 1992
Dec 31;674:27-37. Review. PubMed PMID: 1288368.
Stockton JD, Merkert MC, Kellaris KV. A complex of chaperones and disulfide
isomerases occludes the cytosolic face of the translocation protein Sec61p and
affects translocation of the prion protein. Biochemistry. 2003 Nov
11;42(44):12821-34. PubMed PMID: 14596596.
Kellaris KV. Identification of a disulfide between cysteine 214 and cysteine
277 in the beta subunit of native (Na+ + K+)ATPase. Biochem Biophys Res Commun.
1989 Jul 14;162(1):64-70. PubMed PMID: 2546555.
Should there be more public financing for scientific investigation?
Yes, but also better efficiency by better integration
What is your personal position on the use of animals in scientific investigation?
We should study animals for the sake of the animal itself - we will learn a tremendous amount.
Can you briefly explain the difference between common logic and the scientific method?
The scientific method is reductionist
What is science and what is pseudoscience? Who decides which is which?
science has been blessed by the domain of scientists. Pseudoscience is that which lies outside of what science deems proven. Scientists decided which is which.
What is the role of creativity in the scientific method?
Better yet, what is the role of creativity in science. It is central to paradigm changes and larger discoveries.
What it is the most intriguing scientific question that you would like to see resolved?
Why the rise in chronic disease, and what is the interplay between organisms that leads to disease (pathogenesis) - it is a question of systems balance.
What scientific explanation is there for spirituality? Are religion and science incompatible?
Some in science try to explain spirituality in terms of behavioral needs. It is not much different from trying to explain entanglement using current knowledge (relativitively speaking). Science and religion/spirituality are apparently compatible, as >60% of scientists are self-proclaimed religious/spiritual in practice.
Is there some area of knowledge that is morally unacceptable to you?
knowledge and morality are in separate domains, though one can inform the other.
Is there another way science could be studied in schools?
Yes. Experiential learning. We have a natural affinity for learning, discovery and exploration. Traditional science education often steps away from these. No one's fault, but other opportunities await us.
What is the best way to disseminate science in the mass media?
Discourse and dialog. Inviting everyone to the table. Listening.
Why do two or more scientists often come up simultaneously with the same discovery?
Same reason two or more movie makers come up with a similar plot. Society is poised for this thought, this answer, this area of knowledge or creation.
What is the meaning of life? Is there a scientific answer to this question?
Love. Not currently.
Investigating is to live on the frontier of knowledge. Can you explain that sentiment?
I think it's a collapse of two thoughts. One can investigate the frontier of knowledge. One can investigate all sorts of things - not all of them are on the frontier of knowledge.
What would be your dream to work on for your next research project?
Chronic disease and age-related illness in animals and humans; the interplay between organisms, including bacteria and higher-order animals (it's a dialogue; 'infection' does not occur on an empty slate)
If you could give just one piece of advice to beginning researchers, what would it be?
Be part of the greater whole - 'own' your passion while also being accountable - for what you experience, for what you create, and for how you go about being human.
Livermore CA USA